The Tennessee State Department of Health and CDC are collaborating with public health officials in multiple states and the USDA’s Food Safety and Inspection Service to investigate an ongoing multistate outbreak of E. coli O157:H7 infections.

Frozen pizza that contained pepperoni and was produced by the General Mills company under the brand names of Totino’s or Jeno’s was the likely source of the illness.

As of November 1st, at least 21 confirmed cases of E. coli O157:H7 have been collected. At least 8 people have been hospitalized, and 4 have developed a type of kidney failure known as hemolytic-uremic syndrome.