Today Bioniche Life Sciences Inc. a research-based, technology-driven Canadian biopharmaceutical company, announced that positive results were seen in the three latest University of Nebraska feedlot studies utilizing the E. coli O157:H7 cattle vaccine.
In one study, with cattle receiving three doses of vaccine, there were 73% fewer animals detectably shedding E. coli O157:H7 bacteria in their manure. Another three-dose study analyzed colonization in the terminal rectal junction in the cattle, where the bacteria are known to colonize and reproduce. After vaccination, 97% fewer animals had detectable bacterial colonization. A third study, involving 19 feedlots and 21,691 cattle, demonstrated that the vaccine was effective in commercial feedlot settings. In that study, vaccinated cattle were 75% less likely to have detectable bacterial colonization.
This is the third year of data generated through clinical trials of this vaccine, and we are seeing consistently satisfactory results in terms of its effectiveness in feedlot settings where E. coli O157:H7 bacteria are prevalent. The results of the latest University of Nebraska studies will be published in a peer-reviewed journal later this year.